Liverpool have already won the premier league title but they will face Burnley needing eight points from a possible 12 to equal Manchester City’s record of 100, set in 2017/18.
With four matches left to the end of the season, Mohamed Salah is also desperate to win the Golden Boot for the third consecutive season. The Egyptian scored twice against Brighton last Wednesday to take his tally to 19, just three adrift topscorer, Jamie Vardy.
Burnley are seeking a fourth win in five matches, and a victory would take them above Tottenham Hotspur and Arsenal in the battle for European qualification but they will have a tough task against the champions with an attack of Mane, Firmino and Salah that has produced 250 goals under Jurgen Klopp.
Both sides have met 11 times in the premier league with Liverpool winning nine and drawing one while Burnley won just one.
Liverpool have won 82 per cent of their Premier League meetings with Burnley, their best winning ratio against a side they have faced at least 10 times in the competition. Burnley have won 14 matches this season, equalling their best total in the competition. They last won more in a top-flight campaign in 1974/75, with 17.
The Reds will be without Captain, Jordan Henderson, who has been ruled out of the season with a knee injury.
Defender Dejan Lovren is back in full training and could come into contention for the encounter.
Burnley report no fresh injury concerns, but Ben Mee, Jack Cork, Ashley Barnes and Matt Lowton are expected to miss the rest of the season.
Mohamed Salah vs Nick Pope
Nick Pope has been amazing this season and he is leading the race for the Golden Glove 14 Premier League clean sheets. He could become the first English to win the accolade if he manages it since Joe Hart in 2015/16 for Man City.
However, Salah is determine to finish as topscorer this season and it will be a direct battle between both players.
Virgil van Dijk vs Chris Wood
Van Dijk has made a huge impression at Anfield since he joined Liverpool from Southampton but he will have a tough game against Chris Wood. The Burnley striker returned from injury last time to help the Clarets beat West Ham. It will be an interesting battle between both players.
Liverpool: Alisson Becker; Virgil van Dijk,Joseph Gomez, Andrew Robertson, Trent Alexander-Arnold; Fabinho,Georginio Wijnaldum,Naby Keita; Sadio Mane, Mohamed Salah, Roberto Firmino.
Burnley: Nick Pope; Charlie Taylor, James Tarkowski, Phil Bardsley, Kevin Long, Josh Brownhill; Dwight McNeil, Ashley Westwood, Erik Pieters; Chris Wood, Jay Rodriguez.
Referee: David Coote. Assistants: Marc Perry, Nick Hopton. Fourth official: Martin Atkinson.
Replacement official: James Mainwaring. VAR: Chris Kavanagh. Assistant VAR: Adrian Holmes.
Liverpool 2-1 Burnley