AC Milan Coach Genaro Gatusso will have shuffle things at the back as he has lost two trusted personnel in his backline to injury.
Davide Calabria and Ignazio Abate have been ruled out of AC Milan's Europa League trip to Arsenal on Thursday.
The full-backs were omitted from a 19-man squad named by Gattuso for the second leg, in which Milan will try to overturn a 2-0 deficit.
Milan disclosed that Abate is missing with a calf problem and Calabria struggling with a muscle injury.
Gattuso is already without first-choice right-back Andrea Conti long-term, with the versatile Fabio Borini expected to fill in.
Andre Silva will compete with Patrick Cutrone for a place up front after scoring his first Serie A goal for the club, a dramatic late winner in a 1-0 win over Genoa on Sunday.