The host team will be without the service of Maxi Gomez due to broken foot, and Eliaquim Mangala is doubtful for the clash and he is battling to be fit from a thigh injury.
Former Real Madrid defender Ezequiel Garay will miss the clash as he is out of the season, meanwhile but Manu Vallejo and Cristian Piccini will make the cut after recovering from foot and knee issues respectively.
Rafael Toloi is down with muscular problem, the Brazilian ace is being tipped to return in time for Tuesday’s contest.
HEAD TO HEAD:
Both teams have met twice with Atalanta winning both ties, the meeting at Mestalla will represent their third meeting.
The Spanish team has not been impressive so far this season in their last five games they have only one victory, two ended in a draw and two in defeat including the 4-1 deafeat against Atalanta in the Champions League, Valencia is 7th on the La Liga table.
The Italian team has performed so well in their last five games with all the games ending in a victory in all competition.
They have been able to transform such form to Europe and they have showcase they are capable of competing at the highest level of European football.
POSSIBLE LINE UPS:
Domenech; Wass, Diakhaby, Gabriel, Gaya; Torres, Parejo, Kondogbia, Soler; Rodrigo, Gameiro
Gollini; Palomino, Caldara, Toloi; Gosens, Freuler, De Roon, Hateboer; Pasalic; Zapata, Ilicic
Valencia 0-2 Atalanta.